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a Diagram of human glycyl-tRNA synthetase (brown) with tRNA (green), phosphoaminophosphonic acid-adenylate ester and glycine (ball and sphere with surface) bound at the active site (PDB4KR3). By comparison to glycine (b), glyphosate (c) is unlikely to bind to the active site due to the steric hindrance of its phosphonate group. The structure of the metabolites of glyphosate aminomethylphosphonic acid (d) and glyoxylate (e) is also presented
