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. 2019 Aug 7;17:258. doi: 10.1186/s12967-019-2001-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Growth curves for T-cells expanded in the Quantum system. PBMCs were incubated with anti-CD3/CD28 DynaBeads then seeded in the Quantum system bioreactor at either 85 × 10⁶ (a) or 30 × 10⁶ (b) PBMCs. Five individual donors are shown. Numbers of cells indicates total mononuclear cells at various timepoints enumerated from samples taken from the IC loop following mixing of the entire IC compartment. Final cell numbers are for products enumerated following automated harvest from the Quantum system. D donor