Role |
Development, maintenance, and repair of the extracellular matrix (ECM). |
Origin |
Mesenchymal stem cells |
Volume |
2% of the total volume of articular cartilage. |
Shape, number, and size |
Vary in shape, number, and size, depending on the anatomical regions of the articular cartilage. |
Respond to stimuli |
Respond to a variety of mechanical stimuli and growth factors |
Replication |
Detectable cell division, limited potential for replication |
Synthesis matrix |
Responsible for both the synthesis and the breakdown of the cartilaginous matrix. |
Differentiation |
Highly differentiated cell, highly specialized, metabolically active cells |
Adaption by low oxygen |
Well adapted by low oxygen consumption to conditions |