Fig. 5.

NR1B2 regulate EMT through YAP phosphorylation. a. Western blotting of Vimentin, N-cadherin, E-cadherin, and NR1B2 in SW839 and 786-O cells that express NR1B2 or not. b. Western blotting of YAP, phosphorylated Yap (p-YAP), and NR1B2 in SW839 and 786-O cells. c-d. Western blotting of YAP, phosphorylated Yap (p-YAP), and NR1B2 in SW839(c) and 786-O(d) cells treated with 1 μM ATRA. e-f. Western blotting of the indicated protein in NR1B2 overexpressed SW839 cells(e) or in NR1B2 knock down 786-O cells(f) with or without Yap siRNA. g-h. Migration and invasion assays were performed in overexpression NR1B2 in SW839 and knockdown NR1B2 in 786-O with or without YAP siRNA