Fig. 3.
Atorvastatin prevents aldosterone-induced p47pox activity in WKY VSMCs. Effects of aldosterone (10−7 mol/L) on p47phox translocations from cytosol to the membrane, in the absence and presence of 10−7 mol/L of atorvastatin (60 minutes and 72 hours pre-incubation). Representative immunoblots: p47phox (fractions of membrane and cytosol). Results are mean ± SEM of 5–6 experiments. *P < 0.05, vs. vehicle.