Table 3.
Protective Effect of APOE Variants Against HEV Infection in Non-Hispanic Blacks* in the NHANES III, 1991–1994
Variant | Allele Frequency† (%) | OR (95% CI) | P |
---|---|---|---|
Non-Hispanic whites | |||
APOE ε2 | 8.3 | 1 (reference) | |
APOE ε3 | 76.0 | 0.9 (0.7–1.2) | 0.99 |
APOE ε4 | 15.7 | 0.9 (0.6–1.6) | 0.99 |
Non-Hispanic blacks | |||
APOE ε2 | 10.1 | 1 (reference) | |
APOE ε3 | 67.9 | 0.6 (0.4–0.8) | 0.001 |
APOE ε4 | 22.0 | 0.5 (0.4–0.7) | 0.00004 |
Mexican Americans | |||
APOE ε2 | 3.3 | 1 (reference) | |
APOE ε3 | 85.7 | 0.9 (0.6–1.5) | 0.99 |
APOE ε4 | 11.0 | 0.8 (0.5–1.6) | 0.99 |
Logistic regression analysis within each race/ethnicity group.
Frequencies adjusted using NHANES III genetic sample weight.