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. 2019 Aug 5;25(8):479–488. doi: 10.1089/ten.tec.2019.0088

FIG. 1.

FIG. 1.

Fabrication and Modeling of the Novel and Standard Bioreactor. (A) A fully assembled novel bioreactor. (B, C) A front-viewed 3D model of stable fluid velocity vectors in a novel design bioreactor without bubbles and with, respectively. The bubble highlighted by the arrow is trapped in the channel without disrupting the velocity gradient in the main chamber. (D) A fully assembled standard bioreactor. (E, F) A front-viewed 3D model of stable fluid velocity vectors in a standard design bioreactor without bubbles and with, respectively. Note the significant increase in fluid velocity (exceeding the velocity scale by ∼10-fold, see text) after encountering the bubble (arrow). (G–J) Photographs of the movement of an actual bubble (arrow) in the novel design highlighted by colored liquid. (G, H) Bubble entering the channel. (I, J) A bubble moving through the channel to the back wall. All scale bars are 2.5 cm. 3D, three-dimensional. Color images are available online.