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. 2019 Aug 5;25(8):479–488. doi: 10.1089/ten.tec.2019.0088

FIG. 2.

FIG. 2.

Alginate bead shear modeling. (A–D) The position of alginate beads over 1 s marked every 1/20th of a second in RWV bioreactors rotating counterclockwise under the four conditions defined in the text. The bubble is shown by the red arrows in (C, D). (E) The average fluid shear stress experienced by the beads over the course of the path. The shear stress in the novel design with bubbles is not significantly different from that in the first two instances. (F) The maximum shear stress experienced by the beads during the observed path. (G) Maximum shear values observed in the standard bioreactor with increasing bubble size. Shear stress measurements are detailed in the text. All scale bars are 2.5 cm. *Significant at p < 0.05. NS, not significant; RWV, rotating wall vessel. Color images are available online.