Table 1.

Schematic representation of the sequential isolates from various species chronically infecting the different CF patients examined in this study.

CF patients	Number of sequential isolates with () or without () O-antigen	O-antigen profiles (in Figure 2)	Isolate ribo-patterns (R)/RAPD profiles	Patient clinical outcome	Duration of the chronic infection with the Bcc strain (years)
Burkholderia cenocepacia IIIA
I	3	A1	R08/RAPD01	Infection eradicated	2.6
J	1 10	A2 and A3	R11/RAPD02	Dead *	3.4
O	10	A4	R11/RAPD03	Infection eradicated before death	3
P	3	A5	R13/RAPD04	Infection eradicated before death	2.5
AB	17 29	A6 and A7	R07/RAPD05	Still infected	14.7
AF	2 5 1	A8 and A10 A9	ND/RAPD06 RAPD07	Dead	2.5 0.1
AN	10 21	A11 and A12	R21/RAPD08	Dead	6.8
Burkholderia cenocepacia IIIB
O	8 2	B1 B2	R14/RAPD09 RAPD10	Infection eradicated before death	3.4 0.7
R	12 2 11	B3 and B4	R15/RAPD10	Infection eradicated	7.5
T	6	B5	R16/RAPD11	Infection eradicated before death	1.2
Burkholderia cepacia
D	11	C1	ND/RAPD12	Dead	4.4
N	28	C2	R12	Dead	3.8
O	24	C2	R12	Infection eradicated before death	5.6
AL	10	C1	R19/RAPD12	Infection eradicated	2.2
AP	5	C1	R19	Infection eradicated	2.8
AQ	10	C5	R24	Infection eradicated	2.9
AU	32 2	C3 C4	ND/RAPD12 RAPD13	Still infected	9.6 0.4
Burkholderia contaminans
V	13	D1	R17	Alive	15.2
AF	29	D2	R02	Dead	5.8
Burkholderia multivorans
J	2 6 1	E1 and E2	R9	Dead*	4
Burkholderia dolosa
AR	14	F	ND	Dead	5.5
Burkholderia stabilis
B	4 1	G1 G2	R01/RAPD15 RAPD14	Dead	3.8 0.1
H	8 4	G3 G4	R01/RAPD14 RAPD15	Dead*	2.5 2

Information on the number of sequential clonal isolates in which the OAg is present () or absent () and the corresponding OAg profiles (Figure 2), when present, the ripopatterns of the isolates (Cunha et al., 2003, 2007; Coutinho et al., 2015) and their RAPD profiles (Figure S1) and the duration of the chronic infection and clinical outcome of the infected CF patients (Cunha et al., 2003, 2007; Coutinho et al., 2011; Moreira et al., 2014) is provided. R, Isolate ribopattern; RAPD, Random amplified polymorphism DNA profile (Figure S1); ND, not determined;

^*, cepacia syndrome.