Skip to main content
. 2018 Oct 11;29(9):3796–3812. doi: 10.1093/cercor/bhy260

Figure 4.

Figure 4.

Experience-dependent developmental emergence of sparse representation in L2/3. (A) Percentage of L2/3 excitatory neurons responding to tones or to noise at different developmental stages. ST1, P18–P21; ST2, P25–P28; ST3: P32–P35. N = 5, 5, 5, and 10 mice; 130, 141, 119, and 310 cells, respectively. ***P < 0.001; *P < 0.05, one-way ANOVA and post hoc test. (B) Color maps of TRFs for 4 representative ST1 and adult neurons. (C) Comparison of TRF bandwidth at different stages. N = 44, 22, 15, and 45 cells, respectively. **P < 0.01; *P < 0.05, one-way ANOVA and post hoc test. (D) Percentage of PV inhibitory neurons responding to tones at different stages. P > 0.5, one-way ANOVA test. (E) TRF bandwidth of PV inhibitory neurons at different stages. N = 17, 12, 13, and 75 cells, respectively. P > 0.5, one-way ANOVA test. (F) Left, rearing the animal in a sound-attenuation chamber where noise was applied from P9 to P35. Right, percentage of responding L2/3 excitatory or PV neurons in ST1, noise-reared adult and control adult mice. Bar = SD. Noise-reared animals (n = 5 mice, 107 cells) are different from control adult animals for excitatory neurons (**P < 0.01, t-test). (G) Comparison of TRF bandwidth. N = 23 for excitatory cells and 23 for PV cells in the noise-reared group. *P < 0.05, t-test.