Table 2. Comparative Univariate Analysis of Mortality Between Patients With ADHD and a Group of Controls Without ADHD, Taiwan, 2000 to 2012.
Outcome or Subgroup | Group With ADHD | Group Without ADHD | Estimate, HR (95% CI)a | P Value | ||||
---|---|---|---|---|---|---|---|---|
Deaths, No. | Person-Years, No. | Rate, Deaths/10 000 Person-Years | Deaths, No. | Person-Years, No. | Rate, Deaths/10 000 Person-Years | |||
All cause | ||||||||
Total | 727 | 189 2521 | 3.84 | 3594 | 13 254 591 | 2.71 | 1.42 (1.31-1.54) | <.001 |
Male | 546 | 1 443 000 | 3.78 | 2852 | 10 105 209 | 2.82 | 1.34 (1.22-1.47) | <.001 |
Female | 181 | 449 521 | 4.03 | 742 | 3 149 381 | 2.36 | 1.71 (1.45-2.01) | <.001 |
Suicide | ||||||||
Total | 117 | 1 892 521 | 0.62 | 257 | 13 254 591 | 0.19 | 3.19 (2.56-3.97) | <.001 |
Male | 76 | 1 443 000 | 0.53 | 186 | 10 105 209 | 0.18 | 2.86 (2.19-3.74) | <.001 |
Female | 41 | 449 521 | 0.91 | 71 | 3 149 381 | 0.23 | 4.04 (2.75-5.94) | <.001 |
Unintentional injury | ||||||||
Total | 188 | 1 892 521 | 0.99 | 1090 | 13 254 591 | 0.82 | 1.21 (1.03-1.41) | .01 |
Male | 163 | 1 443 000 | 1.13 | 968 | 10 105 209 | 0.96 | 1.18 (1.01-1.39) | .03 |
Female | 25 | 449 521 | 0.56 | 122 | 3 149 381 | 0.39 | 1.44 (0.93-2.21) | .15 |
Homicide | ||||||||
Total | 14 | 1 892 521 | 0.07 | 48 | 13 254 591 | 0.04 | 2.04 (1.13-3.70) | .007 |
Male | 11 | 1 443 000 | 0.08 | 41 | 10 105 209 | 0.04 | 1.88 (1.01-3.65) | .02 |
Female | 3 | 449 521 | 0.07 | 7 | 3 149 381 | 0.02 | 3.00 (0.78-11.61) | .25 |
Natural cause | ||||||||
Total | 408 | 1 892 521 | 2.17 | 2199 | 13 254 591 | 1.67 | 1.30 (1.17-1.45) | <.001 |
Male | 295 | 1 443 000 | 2.07 | 1656 | 10 105 209 | 1.65 | 1.25 (1.11-1.42) | <.001 |
Female | 113 | 449 521 | 2.51 | 543 | 3 149 381 | 1.72 | 1.46 (1.19-1.79) | <.001 |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; HR, hazard ratio.
All-cause mortality was analyzed by the log-rank test; specific-cause mortality was analyzed by the modified log-rank test using the Fine and Gray13 method.