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. 2019 Jun 10;3(3):pkz038. doi: 10.1093/jncics/pkz038

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© The Author(s) 2019. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contactjournals.permissions@oup.com.

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Figure 1. — Trends in overall cancer incidence rates by sex, age group, and year of diagnosis, Surveillance, Epidemiology, and End Results 9 database registries, 1975–2015. A) Annual overall cancer incidence rates, age-adjusted to the 2000 US standard population, and annual percent change (APC) for each joinpoint segment for women by age group at diagnosis. B) Annual overall cancer incidence rates, age-adjusted to the 2000 US standard population, and APC for each joinpoint segment for men by age group at diagnosis. The APC for each joinpoint segment is provided above or below the trend line. *Statistically significant APCs (H₀: APC = 0; P < .05 for a two-sided test based on the t distribution).