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. 2019 Jun 10;3(3):pkz038. doi: 10.1093/jncics/pkz038

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© The Author(s) 2019. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contactjournals.permissions@oup.com.

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Figure 3. — Site-specific cancer incidence trends for women by age group at diagnosis based on the annual percent change (APC) after the most recent joinpoint inflection point, Surveillance, Epidemiology, and End Results 9 database registries, 1975–2015. Incidence rates are age-adjusted to the 2000 US standard population. Cancer types are classified based on SEER’s site recode International Classification of Diseases for Oncology, third revision/World Health Organization-2008 variable: bladder = urinary bladder; brain/CNS = brain and other central nervous system; cervical = cervix uteri; kidney = kidney and renal pelvis; liver = liver and intrahepatic bile duct; lung = lung and bronchus; oral = oral cavity and pharynx; uterine = corpus and uterus, not otherwise specified. Positive APCs, which indicate increasing incidence over time, are in red (color shading darkens with increasing values); negative APCs, which indicate decreasing incidence over time, are in blue. Statistically significant APCs (H0: APC = 0; P < .05 for a two-sided test based on the t distribution) are bold. CI = confidence interval.