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. Author manuscript; available in PMC: 2019 Sep 6.
Published in final edited form as: Nat Med. 2019 Mar 6;25(3):487–495. doi: 10.1038/s41591-019-0381-y

Fig. 1 |. Study design.

Fig. 1 |

Peripheral blood samples from 135 healthy individuals (63 young and 72 older adults) were collected over 9years. The snapshot cohort included 18 individuals that were profiled at the end of the seventh year (2013) by cell subset phenotyping, whereas the entire ongoing cohort was profiled annually for cell subset phenotyping, functional responses of cells to cytokine stimulations, and whole-blood gene expression.