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. Author manuscript; available in PMC: 2019 Sep 6.
Published in final edited form as: Nat Med. 2019 Mar 6;25(3):487–495. doi: 10.1038/s41591-019-0381-y

Extended Data Figure 5 |. Classification scheme of cell subsets based on their dynamics.

Extended Data Figure 5 |

Cell subsets identified as significantly age dependent in a combinatorial analysis across years were filtered based on annual-change data quality. Cell subsets exhibiting an annual change not significantly different from 0 were classified as fluctuating, whereas those exhibiting a significant nonzero annual change were subjected to an additional analysis testing the relationship of their annual change with baseline frequencies. Cell subsets with a nonsignificant association were classified as linear whereas those exhibiting a significant association were classified as asymptotic and were subjected to three additional tests analyzing the significance of their identified attractor point locations.