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. Author manuscript; available in PMC: 2019 Sep 6.
Published in final edited form as: Nat Med. 2019 Mar 6;25(3):487–495. doi: 10.1038/s41591-019-0381-y

Fig. 6 |. IMM-AGE score predicts all-cause mortality risk beyond well-established risk factors.

Fig. 6 |

a, Kaplan-Meier overall survival curves for Framingham, Heart Study participants stratified based on median values of their IMM-AGE scores adjusted to cardiovascular risk factors and cardiovascular disease. Yellow and blue curves correspond to individuals with low and high IMM-AGE scores, respectively (P = 0.018, n = 2,290, two-sided log-rank test). b, Interaction between age and life history creates an immunological landscape dictating the composition of the cellular immune system.