Skip to main content
. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Biomed Pharmacother. 2019 Jul 2;117:109179. doi: 10.1016/j.biopha.2019.109179

Figure 3.

Figure 3.

Ethanol treatment in adult zebrafish activated genes associated with superoxide, hydrogen peroxide generation and regulation of redox balance in the liver. (A) Ethanol exposure increased relative mRNA expression in cyp2p6, cyp2y3, nox1, nox2 and nox5 in the liver. (B) Relative mRNA expression of nrf2, sod2 and genes associated with redox balance. (C) ROS quantification, (D) GSH level and (E) GSH/GSSG ratio were measured in the liver of control and 0.2% ethanol exposed groups. (F) Relative mRNA expression of genes associated with GSH synthesis including glutathione synthase (gss), glutamate-cysteine ligase, catalytic subunit (gclc), glutamate-cysteine ligase, modifier subunit (gclm), cystathionine b-synthase a (cbsa), betaine--homocysteine S-methyltransferase (bhmt). Error bars indicate standard deviation of the mean. * p<0.05, ** p<0.005.