Table 1. Statistical analysis of semi-quantitative cardiac scoring.
Strain | Treatment | Sex | Time | Sex X Trt | Trt X timepoint |
---|---|---|---|---|---|
CC 01 | 0.076 (0.041) | −0.034 (0.034) | −0.045 (0.034) | −0.019 (0.048) | 0.14 (0.048) * |
CC 10 | 0.067 (0.031) | −0.031 (0.026) | 0.052 (0.027) | 0.099 (0.036) * | 0.021 (0.037) |
CC 11 | 0.072 (0.02) ** | −0.039 (0.016) | 0.009 (0.016) | 0.024 (0.023) | 0.021 (0.023) |
CC 19 | 0.138 (0.025) *** | −0.028 (0.02) | 0.034 (0.02) | 0.015 (0.028) | 0.075 (0.029) * |
CC 32 | 0.172 (0.025) *** | −0.029 (0.021) | 0.112 (0.021) *** | −0.038 (0.029) | −0.01 (0.029) |
CC 37 | −0.003 (0.028) | −0.022 (0.023) | 0.036 (0.023) | 0.114 (0.031) ** | 0.038 (0.031) |
CC 40 | 0.136 (0.04) ** | 0.03 (0.033) | −0.01 (0.033) | 0.033 (0.052) | 0.153 (0.061) |
CC 41 | 0.006 (0.031) | −0.069 (0.03) | 0.019 (0.03) | 0.178 (0.039) *** | 0.097 (0.039) * |
CC 42 | 0.094 (0.032) * | −0.007 (0.024) | −0.018 (0.024) | 0.009 (0.036) | 0.131 (0.036) ** |
CC 51 | 0.103 (0.033) * | −0.022 (0.027) | 0.015 (0.027) | 0.024 (0.037) | −0.028 (0.037) |
Linear model examining main effects (sex, treatment;Trt and time) and two additional treatment interactions (with sex and time). All values are given as estimates (standard error). Benjamini-Hochberg adjusted p-values are indicated as asterisks.
P < 0.05.
P < 0.01.
P < 0.001.
CC040†: all but two animals in the chronic group died prematurely.