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. 2019 Jun 5;140(6):500–513. doi: 10.1161/CIRCULATIONAHA.119.041059

Figure 6.

Figure 6.

Hhipl1 deficiency reduces smooth muscle cell content in Hhipl1−/−;Ldlr−/−atherosclerotic lesions. Representative photomicrographs of atherosclerotic lesion components in Hhipl1+/+;Ldlr−/− and Hhipl1−/−;Ldlr−/− mice. A, Oil red O (ORO) staining for lipids; C, MOMA-2 staining for macrophages; E, anti–alpha smooth muscle actin (SMA) staining for smooth muscle cells; and (G) Masson trichrome for collagen. Bars, 200 μm. The percentage content (average of 9 sections per animal) of (B) lipids, (D) macrophages, (F) smooth muscle cells, and (H) collagen (n=6 per group). Error bars represent mean±CI. HHIPL1 indicates hedgehog interacting protein-like 1. **P≤0.01.