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. 2019 Feb 15;11(9):2226–2242. doi: 10.1002/cctc.201801829

Scheme 3.

Scheme 3

The diversification of ent‐kaurene (2) by four P450 enzymes occurring in the Gibberellin biosynthetic pathway.60,61 The positions accessible by different P450s are marked in red and the enzymes with their corresponding reactions are colour‐coded. One of the most abundant metabolites with known potency is shown in the box with the introduced functional groups coloured in red.