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. 2019 Jul 29;15(7):e1007935. doi: 10.1371/journal.ppat.1007935

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© 2019 Doyle et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A) Unbiased viSNE plot of CyTOF data from R848-stimulated LMCs of 3 HCV⁺ individuals. Major immune subsets were manually gated and mapped onto viSNE plot. (B) Heatmap of normalized mean signal intensity (nMSI) of all cytokines/chemokines for each immune subset. (C) Histogram of signal intensity of IFNα for each immune subset; insert is percent pDCs expressing IFNα. (D) Manual gating of IFNα⁺ pDCs for 3 HCV⁺ individuals both with and without stimulation.