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. 2019 Jul 29;13(7):e0007570. doi: 10.1371/journal.pntd.0007570

Table 1. Gene sets enriched in adherent and swimming form C. fasciculata.

Enriched in adherent
NAME KEGG Size NES FDR
Seleno compound metabolism ec00450 51 2.057 0.000
Biosynthesis of ansamycins ec01051 55 1.914 0.003
Flavonoid biosynthesis ec00941 55 1.910 0.002
Aminoacyl-tRNA biosynthesis ec00970 31 1.910 0.002
Porphyrin and chlorophyll metabolism ec00860 80 1.903 0.002
Biosynthesis of 12-14-and16-membered macrolides ec00522 56 1.902 0.001
Polycyclic aromatic hydrocarbon degradation ec00624 55 1.809 0.006
Stilbenoid diaryl heptanoid and gingerol biosynthesis ec00945 58 1.804 0.005
Anthocyanin biosynthesis ec00942 71 1.736 0.012
Ubiquinone and other terpenoid-quinone biosynthesis ec00130 79 1.727 0.012
Histidine metabolism ec00340 68 1.717 0.012
Insect hormone biosynthesis ec00981 87 1.669 0.019
Cysteine and methionine metabolism ec00270 96 1.580 0.037
Enriched in swimmers
NAME KEGG Size NES FDR
Putative paraflagellar rod proteins NA 46 -2.230 0.001
Valine leucine and isoleucine degradation ec00280 33 -2.090 0.001
Fatty acid degradation ec00071 36 -2.080 0.001
Caprolactam degradation ec00930 15 -1.950 0.003
Starch and sucrose metabolism ec00500 28 -1.920 0.004
Oxidative phosphorylation ec00190 55 -1.840 0.01
Fatty acid elongation ec00062 20 -1.820 0.012
Glycerolipid metabolism ec00561 39 -1.760 0.02
Propanoate metabolism ec00640 50 -1.720 0.026
Biosynthesis of unsaturated fatty acids ec01040 22 -1.710 0.028

The pathway or gene set name, KEGG pathway ID (where applicable), number of genes (Size), GSEA Normalized Enrichment Score (NES), and False Discovery Rate q-value (FDR) are provided. We considered FDR < 0.05 as enriched. Positive and negative NES scores indicate gene set enrichment in adherent or swimming form cells, respectively.