Table 1. Significant eQTLs for adipose tissue IGF2 gene expression in the 3BCs animals.
Region | Chr | Start-End Positions | Size (Mb) | SNPs N | Start-End SNPs | Most Significant SNP | P-value | Type of eQTL | Candidate genes* |
---|---|---|---|---|---|---|---|---|---|
1 | 2 | 0,145,257–11,580,559 | 11.43 | 21 | rs81306755- rs81278022 | IGF2 | 2.07E-15 | cis/trans | IGF2 and SF1 |
2 | 8 | 121,609,989–128,426,767 | 6.82 | 2 | rs80913047- rs81404614 | rs80913047 | 2.59E-07 | trans |
Chromosomal location is based on S. scrofa 11.1 assembly. Positions start and end refer to the eQTL interval. Gene annotation was performed considering one additional Mb at the start and at the end of the eQTL interval. Number of SNPs corresponds to the SNPs within the eQTL interval. P-value corresponds to the most significant SNP. For the cis-eQTL only the analyzed gene was considered.
*Genes with functions related to IGF2.