Fig. 4.

Classification accuracy for miRNA combinations. The plot depicts the average receiver operating characteristics (ROC) for the 93 best multimarker models of the validated miRNAs. The faint lines are the individual ROC curves for the top-multimarker models (color coded based on the number of miRNAs that contributed to the model). Bold solid lines are the empirical averages of the individual ROC curves. Dashed curves are binormal estimates of the average. The mean area under the curve (AUC) for the averaged ROC curves are presented. Note that some of the individual ROC curves generated from 6 miRNAs (faint orange lines) or 7 miRNAs (faint blue lines) have AUCs that exceed 0.80.