Table 1. Descriptive data from demographics, reproductive and lifetime (up to age 80 years) breast cancer risk estimates variables in the FHS-7 positive and FHS-7 negative groups.
| FHS-7 positive (n=846) | FHS-7 negative (n=892) | |||
|---|---|---|---|---|
| N (%) | Mean (SD) | N (%) | Mean (SD) | |
| Age at assessment | - | 43.5 (12.2) | - | 50.9 (9.1) |
| BMI | - | 28.0 (5.6) | - | 28.7 (5.8) |
| Age at menarche | - | 12.7 (1.7) | - | 13.0 (1.7) |
| Parity | ||||
| One or more children | 753 (89.0) | - | 828 (92.8) | - |
| Age at birth of first child | - | 21.5 (5.0) | 21.7 (5.2) | |
| Reproductive Status | ||||
| Post-menopausal | 295 (34.9) | - | 449 (50.3) | - |
| Age at menopause | - | 46.9 (5.5) | - | 46.8 (5.5) |
| Hormone replacement therapy | 69 (8.2) | - | 97 (10.9) | - |
| Endogenous hormone exposure (ys) | - | 3.3 (3.1) | - | 3.0 (3.7) |
| Consanguinity+ | 58 (7.0) | - | 52 (5.8) | - |
| Gail | 9,9 (4,4) | 6,5 (2,0) | ||
| < 10% | 524 (61,9) | 846 (94,8) | ||
| 10% - 20% | 309 (36,5) | 46 (5,2) | ||
| > 20% | 13 (1,5) | 0 (0,0) | ||
| Tyrer-Cuzick | 10,8 (4,9) | 6,0 (2,6) | ||
| < 10% | 411 (48,7) | 935 (93,6) | ||
| 10% - 20% | 394 (46,7) | 55 (6,2) | ||
| > 20% | 39 (4,6) | 2 (0,2) | ||
(+) Evidence of consanguinity within family, regardless of relationship to the proband. BMI: Body mass index. SD: Standard deviation.