Figure 1. Candidate biomarkers that have been followed longitudinally in SCA3/MJD subjects. (A) Summary of the longitudinal data obtained for eotaxin and Scale for Assessment and Rating of Ataxia (SARA); sensory nerve action potential (SNAP) amplitudes of sural nerves and International Cooperative Ataxia Rating Scale (ICARS); and short-interval intracortical inhibition (SICI) of motor evoked potentials and ICARS. (B) Cohen effect sizes, when available or when estimation was possible.
