Table 3. Approved enzyme replacement therapies.

Disease	Generic name	Brand name	Dose	Delivery
Gaucher type I	Imiglucerase	Cerezyme®	60 Units/kg (every other week)	I.V. infusion
	Taliglucerase alfa	Elelyso®	60 Units/kg (every other week)
	Velaglucerase alfa	Vpriv®	60 Units/kg (every other week)
Fabry disease	Agalsidase beta	Fabrazyme®	1 mg/kg (every other week)	I.V. infusion
	Agalsidase alfa	Replagal®	0.2 mg/kg (every other week)
Pompe disease	Alglucosidase alfa	Myozyme®	20 mg/kg (every other week)	I.V. infusion
	Alglucosidase alfa	Lumizyme®
MPS I - Hurler, Hurler-Scheie and Scheie	Laronidase	Aldurazyme®	0.58 mg/kg (once per week)	I.V. infusion
MPS II – Hunter Syndrome	Idursulfase	Elaprase®	0.5 mg/kg (once per week)	I.V. infusion
MPS VI - Maroteaux-lamy syndrome	Galsulfase	Naglazyme®	1 mg/kg (once per week)	I.V. infusion
MPS IVA – Morquio A syndrome	Elosulfase alfa	Vimizim®	2 mg/kg (once per week)	I.V. infusion
Lysosomal acid lipase deficiency	Sebelipase alfa	Kanuma®	1 mg/kg (every other week)	I.V. infusion
Late infantile neuronal ceroid lipofuscinosis type 2 (CLN2)	Cerliponase alfa	Brineura®	300 mg (every other week)	Intraventricular
MPS VII – Sly syndrome	Vestronidase alfa	Mepsevii®	4 mg/kg (every other week)	I.V. infusion