Table 3.
Recurrence rate in women with endometrioid-type endometrial carcinoma at intermediate risk (IAG2G3 and IBG1G2) according to diagnosis period, the women's characteristics, cancer stage, adjuvant radiotherapy and surgery staging, with or without lymphadenectomy.
| Characteristics | Recurrence |
||||
|---|---|---|---|---|---|
| No (n = 175) |
Yes (n = 14) |
p* | |||
| n | % | n | % | ||
| Period of diagnosis | |||||
| 1990–1998 | 34 | 19.4 | 9 | 64.3 | |
| 1999–2008 | 76 | 43.4 | 3 | 21.4 | |
| 2009–2014 | 65 | 37.2 | 2 | 14.3 | 0.002 |
| Age-group (in years) | |||||
| <50 | 11 | 6.3 | 1 | 7.1 | |
| 50–59 | 57 | 32.6 | 2 | 14.3 | |
| 60–69 | 77 | 44.0 | 8 | 57.2 | |
| ≥70 | 30 | 17.1 | 3 | 21.4 | 0.465 |
| BMI (kg/m2) | |||||
| <35.0 | 119 | 72.1 | 11 | 78.6 | |
| ≥35.0 | 46 | 27.9 | 3 | 21.4 | 0.454 |
| Missing information | 10 | ||||
| Comorbidities§ | |||||
| Yes | 116 | 68.6 | 10 | 71.4 | |
| No | 53 | 31.4 | 4 | 28.6 | 0.546 |
| Missing information | 6 | ||||
| Stage (FIGO) | |||||
| IA G2 | 95 | 54.3 | 5 | 35.7 | |
| IA G3 | 11 | 6.3 | 5 | 35.7 | |
| IB G1 | 30 | 17.1 | 1 | 7.1 | |
| IB G2 | 39 | 22.3 | 3 | 21.4 | 0.009 |
| Radiotherapy | |||||
| EBRT (±brachytherapy) | 79 | 45.1 | 10 | 71.4 | |
| Brachytherapy/none | 96 | 54.9 | 4 | 28.6 | 0.052 |
| Lymphadenectomy | |||||
| Yes | 82 | 46.9 | 12 | 85.7 | |
| No | 93 | 53.1 | 2 | 14.3 | 0.004 |
FIGO: International Federation of Gynecology and Obstetrics. EBRT: external beam radiotherapy. BMI: body mass index.
*
Chi-square test or Fisher’s exact test.
§
Diabetes mellitus and/or systemic arterial hypertension and/or cardiovascular disease.