Table 1.
Patient characteristics and cycle specifics in the two study groups.
| Parameter | Control n = 67 | PCOS n = 39 | P value |
|---|---|---|---|
| Female age | 32.75 ± 5.06 | 31.13 ± 5.19 | 0.12 |
| BMI | 20.51 ± 2.34 | 20.72 ± 2.69 | 0.68 |
| Basal FSH (IU/l) | 7.43 ± 6.79 | 6.05 ± 1.47 | 0.21 |
| Basal LH (IU/l) | 5.49 ± 2.27 | 7.77 ± 5.44 | 0.02 |
| Basal estradiol (pg/ml) | 40.6 ± 23.86 | 34.92 ± 22.7 | 0.23 |
| AMH (ng/ml) | 3.25 ± 2.25 | 9.67 ± 5.85 | 0.001 |
| Starting dose of FSH | 245.15 ± 31.15 | 229.49 ± 33.38 | 0.02 |
| Total dose of FSH | 2005.60 ± 379.69 | 1820.69 ± 332.06 | 0.01 |
| Estradiol on day of hCG (pg/ml) | 1971.26 ± 1007.39 | 3247.1 ± 1992.0 | 0.001 |
| Nr. of stimulation days | 8.31 ± 1.02 | 8.10 ± 0.82 | 0.27 |
| Nr. of retrieved oocytes | 11.48 ± 5.51 | 18.85 ± 9.41 | 0.001 |
| Nr. of mature oocytes | 9.51 ± 4.7 | 14.97 ± 7.43 | 0.001 |
| Oocyte maturation rate | 83.11 ± 14.74 | 81.24 ± 12.92 | 0.51 |
| Fertilization rate | 79.74 ± 16.8 | 82.24 ± 12.63 | 0.42 |
| Good quality embryo rate (Grade A + B) | 77.86 ± 19.28 | 74.17 ± 18.06 | 0.33 |
| Nr. of Blastomere at day 2 | 3.89 ± 0.89 (449) | 4.01 ± 1.13 (402) | 0.09 |
| Low fragmentation at day 2(< 10%) | 78.6% (353) | 76.4% (307) | 0.35 |
| Nr. of transferred embryos | 2.49 ± 0.64 | 2.46 ± 0.76 | 0.82 |
| Biochemical pregnancy rate | 38.8% (26) | 56.4% (22) | 0.08 |
| Clinical pregnancy rate | 32.8% (22) | 46.2% (18) | 0.17 |
| Implantation rate | 17.41 ± 28.01 | 23.07 ± 26.93 | 0.31 |
| Multiple pregnancy rate | 7.5% (5) | 2.6% (1) | 0.29 |
PCOS: Polycystic Ovary Syndrome; BMI: Body Mass Index; FSH: Follicle Stimulating Hormone; LH: Luteinizing Hormone; AMH: Anti-Mullerian Hormone; Nr.: number.