Fig. 1.

General strategy for the BCT-based screening program. The patient population (n = 1000) comprises patients who come to the medical center for a hip CT (for any indication) and who have not had a recent DXA and otherwise qualify for an osteoporosis diagnostic screen. The assigned probability of hip fracture for any individual had four values (A–D), which depended on the background risk (no testing or no test result), the test results (positive or negative) and, for those who tested positive, whether or not treatment was initiated. Variables in the analysis were the level of fracture risk of the underlying population (the background risk), the proportion of patients testing positive who went on treatment, the treatment duration, and the sensitivity and specificity of the test. FX = fracture.