Table 3.

One-Way Sensitivity Analysis on Changing Patient Adherence to Treatment and the Duration of Treatment, for BCT and Usual Care Relative to No Screening and for BCT-UC

			Women (n = 1000)				Men (n = 1000)
Treatment-related parameters	Parameter value	Test	Savings ($1000)	Hip fracture averted	QALY gained	Breakeven BCT cost ($)	Savings ($1000)	Hip fracture averted	QALY gained	Breakeven BCT cost ($)
Adherence to treatment	0.3	BCT	92	3.4	2.49		−30	1.2	0.95
		UC	78	2.2	0.91		0	0.2	0.07
		BCT-UC	14	1.3	1.59	116	−30	1.1	0.88	67
	0.5a	BCT	200	5.5	4.06		7	2.0	1.56
		UC	88	2.4	1.11		1	0.2	0.08
		BCT-UC	113	3.1	2.95	225	7	1.9	1.48	107
	0.7	BCT	308	7.5	5.62		44	2.8	2.16
		UC	97	2.6	1.31		1	0.2	0.09
		BCT-UC	211	4.9	4.31	334	43	2.6	2.07	148
Years of treatment	1	BCT	134	4.1	3.32		−13	1.5	1.27
		UC	76	2.1	0.98		0	0.2	0.07
		BCT-UC	59	2.0	2.33	165	−13	1.3	1.20	86
	2a	BCT	200	5.5	4.06		7	2.0	1.56
		UC	88	2.4	1.11		1	0.2	0.08
		BCT-UC	113	3.1	2.95	225	7	1.9	1.48	107
	3	BCT	245	6.5	4.48		20	2.4	1.72
		UC	94	2.6	1.17		1	0.2	0.08
		BCT-UC	151	3.9	3.31	268	19	2.2	1.64	121

Adherence to treatment refers to the proportion of the patients who test positive that go on treatment. Negative values of savings indicate the strategy is not cost saving (see text for associated values of incremental cost-effectiveness ratios). See Table 2 for additional legends.

BCT = biomechanical computed tomography; UC = usual care; BCT-UC = BCT relative to UC.

^aBase case.