Table 2.
Characteristics of the IVF cycle.
| Characteristics | Thalassemia | Unaffected | p |
|---|---|---|---|
| n = 21 | n = 105 | ||
| Total number of follicles ≥ 11 mm | 9.5 ± 7.2 | 11.0 ± 7.2 | 0.39 |
| N. of oocytes retrieved | 6.0 ± 6.2 | 8.4 ± 6.5 | 0.12 |
| N. suitable oocytesa | 5.5 ± 6.0 | 6.1 ± 4.7 | 0.60 |
| N. of women with no suitable oocytes | 1 (5%) | 3 (3%) | 0.52 |
| Techniqueb | 0.79 | ||
| Classical IVF | 5 (25%) | 31 (30%) | |
| ICSI | 15 (75%) | 71 (70%) | |
| N. cleavage embryosb | 2 [1–5] | 3 [1–5] | 0.51 |
| No viable cleavage embryosb | 1 (5%) | 5 (5%) | 1.00 |
| N. top quality embryosb | 1 [0–4.75] | 2 [1–4] | 0.72 |
| No top quality embryosb | 12 (60%) | 78 (77%) | 0.16 |
| Embryo transferc | 0.55 | ||
| Cleavage stage | 14 (74%) | 76 (80%) | |
| Blastocyst stage | 5 (26%) | 19 (20%) | |
| Total N. of transfersc | 0.83 | ||
| 1 | 13 (68%) | 71 (75%) | |
| 2 | 4 (21%) | 15 (16%) | |
| ≥3 | 2 (11%) | 9 (9%) | |
| Clinical pregnancyd | 7 (33%) | 37 (35%) | 1.00 |
| Live birthd | 4 (19%) | 34 (32%) | 0.30 |
Data are repoorted as mean ± SD or medain [interquartile range] or number (percentage).
“Suitable oocytes’’ include metaphase II oocytes and type 1 cumulus-oocyte complex according to the European Society for Human Reproduction and Embryology Istanbul Consensus Conference, 2011.
Top quality embryo was defined as 4-cells embryo on day 2 or 8-cells embryo on day 3, with a relative degree of fragmentation 10%.
All clinical pregnancies were singletons.
Suitable oocytes refer to metaphase II oocytes and type 1 cumulus-oocyte complex according to the European Society for Human Reproduction and Embryology Istanbul Consensus Conference, 2011.
Data refer to subjects retrieving at least one suitable oocyte (n = 20 and 102 for exposed and unexposed women, respectively).
Data refer to patients performing embryo transfer (95 controls and 19 cases).
Data include both pregnancies obtained with fresh and frozen embryo transfers.