Table 1.

Summary of reported ocular adhesives and their efficiency in sealing an ocular leak.

Category	Leakage pressure (mmHg)	Wound type	Ex vivo model	Refs
Octyl 2-cyanoacrylate	55.13 ± 10.46	5,2-mm full-thickness central corneal lacerations on porcine	porcine	[187]
Nylon 10–0 suture	52.37 ± 7.16
n-Butyl cyanoacrylate	51.2 ± 15.0	2.5-mm uniplanar corneal incision	rabbit	[53]
Methoxypropyl cyanoacrylate	65.2 ±14.5
Fibrin glue	17.5 ± 5.2
Nylon 10–0 suture	15.6 ± 5.2
PEG(3400)-DA with ([G2]- (Lys)3 -Cys4 )	184 ± 79	3-mm clear corneal linear incision	chicken	[91]
Suture group	54 ± 16
PEG(3400)-DA with ([G2]- (Lys)3 -Cys4 )	142 ± 22	2.75-mm clear corneal cataract incisions	Human	[188]
Non-sealed wound	77 ±14
[G1]-PGLSA-MA)2 -PEG	171 ± 44	4.1-mm linear laceration	chicken	[78]
Suture group	90 ± 18
[G1]-PGLSA-MA)2 -PEG	109.6 ± 82.7	4.1-mm linear laceration	Human	[98]
Suture group	78.7 ± 27.8
CS-PEG + CV	35	22-mm linear laceration	Porcine	[9]
BSA-ce6	357 ± 25	6-mm full-thickness central corneal incision	Rat	[131]
BSA-JG	430 ± 36
Non-sealed group	193 ± 6
Laser-soldering collagen patch	3.62 ± 3.09	3.0-mm uniplanar peripheral oblique corneal wound	Rabbit	[149]
Suture group	33.44 ± 9.38
Non-sealed group	125.2 ± 9.85
Laser-soldering collagen patch	101.4 ± 29.92	2.85-mm straight keratome
Suture group	82.7 ± 6.55
Non-sealed group	1.7 ± 0.13