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A. Marked thrombocytopenia was noted within 5 minutes in all xenoperfusions while platelet counts remained stable in the anhepatic controls. B. Subgroup analysis showed no difference with or without the drug regimen in the GalTKO.hCD46.Neu5GcKO cohort (Groups 2A and 2B). Platelet counts were lower in the GalTKO.hCD46 group with the drug regimen compared to without (Groups 1A and 1B) (p=0.0083).
