Table 1.

Sensitivity and positive predictive value for CDW algorithm using CCR cohort as gold standard to identify HIV-infected patients using VA healthcare nationwide (2000–2010).

		Proportion of HIV+ from CCR accurately detected as HIV+ by CDW algorithm			Proportion of patients identified by CDW algorithm accurately classified as HIV+ from CCR
CDW Algorithm	In CCR & CDW (TP)	Not in CDW/In CCR (FN)	In CCR (TP+FN)	Sensitivity (TP/TP+FN) (95% CI)	Not in CCR/ In CDW (FP)	In CDW (TP+FP)	Positive Predictive Value (TP/TP+FP) (95% CI)
1 or more CDW criteria for HIV diagnosis	35,882	1,327	37,209	96.4% (96.2%−96.6%)	29,353	65,235	55.0% (54.6%−55.4%)
2 or more CDW criteria for HIV diagnosis	35,424	1,785	37,209	95.2% (95.0%−95.4%)	2,472	37,896	93.5% (93.2%−93.7%)
3 CDW criteria for HIV diagnosis	31,388	5,821	37,209	84.4% (84.0%−84.7%)	606	31,994	98.1% (97.9%−98.3%)

Abbreviations: CCR-Clinical Case Registry, CDW-Corporate Data Warehouse, CI-confidence interval, FN-false negative, TP-true positive

CDW criteria include: positive HIV lab tests; HIV-specific medications; ICD-9 diagnostic codes for HIV