Table 2.
Architectural Features | Cytoplasmic Quantity | Hyaline Globules | Nuclear Size Variation | Nuclear Shape | Chromatin Pattern | Nuclear Contours | Nucleoli – Number | Nucleoli – Size | Nucleoli - Location | Mitoses | Apoptosis | Necrosis | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case 1 | 3D, T, P, S | S | − | M | R | C | G, M | 1 | P | C | + | + | − |
Case 2 | 3D | S | − | M | R | V | G, M | >1 | I | P | − | − | − |
Case 3/4 | 3D, T, S | S | + | P | R | C | G, M | >1 | I | P | + | + | − |
Case 5 | 3D, T, S | S | + | M | R | NA | G | >1 | I | P | + | + | − |
Case 6 | 3D | S | − | M | R | V | G, M | >1 | P | P | − | − | − |
Case 7 | 3D, T, P, S | S | + | M | R, F | C | G | − | − | − | + | − | − |
Case 8 | 3D, P, S | M | − | P | R | NA | G | 1 | P | C | − | − | − |
Architectural Features: 3D = 3D Overlapping Clusters; T = Tubular Formations; P = Papillary Formations; SC = Cellular Discohesion/Single Cells
Cytoplasmic Quantity: S = Scant; M = Moderate
= present
= absent
NA = not assessable
Nuclear Size Variation: M = monomorphic; P = moderately pleomorphic (2x size variation)
Nuclear Shape: R = round/oval; F = fusiform
Chromatin Pattern (when assessable): C = coarse; V = vesicular
Nuclear Contours: G = grooves/indentations; M = molding
Nucleoli – Number: - = not seen; 1 = single; >1 = multiple
Nucleoli – Size (when present): I = inconspicuous; P = prominent
Nucleoli - Location (when present): C = central; P = peripheral