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. Author manuscript; available in PMC: 2020 Aug 6.
Published in final edited form as: Cell Metab. 2019 Jun 13;30(2):329–342.e5. doi: 10.1016/j.cmet.2019.05.015

Figure 1. Plasma eNAMPT levels are reduced with age in both mice and humans and predicts remaining lifespans of individual mice.

Figure 1.

(A) Plasma eNAMPT levels of female and male mice at 6 and 18 months of age (n=5).

(B) Plasma eNAMPT concentrations of female and male mice at 6 and 18 months of age over a 24-hr period (n=5 per time point per age). The differences between plasma eNAMPT levels at 6 and 18 months of age were assessed by two-way repeated measures ANOVA, and the age effects were significant in both males and females (p<0.05).

(C) Plasma eNAMPT levels of mice and humans across different age groups (n=9 for mice; n=13 for humans).

(D) Relationship of plasma eNAMPT levels and the remaining lifespans of individual mice (n=8). eNAMPT levels were measured at 26-28 months of age.