Table 1.

Characteristics of RA patients at the time of study enrollment^a

	Total (n = 1,460)	No psychiatric diagnosis (n = 944)	Depression/Anxiety Without PTSD (n = 346)	PTSD (n = 170)	P value^b
Sociodemographics
Age at enrollment, years	63.7 ± 11.3	64.9 ± 11.5	62.4 ± 11.4	59.3 ± 8.0	<0.001
Men, %	90.8	91.6	88.7	90.6	0.28
White, %	77.9	79.1	78.3	70.6	0.05
≥HS education, %	84.4	84.5	82.5	87.6	0.35
Other factors
Comorbidity count (0 to 8)	1.8 ± 1.6	1.6 ± 1.5	2.3 ± 1.7	2.3 ± 1.6	<0.001
Smoking status, %					<0.001
Never	20.4	21.7	19.7	15.3
Former	52.3	54.5	52.6	40.0
Current	27.2	23.9	27.8	44.7
BMI (kg/m²)	28.3 ± 5.7	28.1 ± 5.7	28.1 ± 5.7	29.4 ± 5.9	0.05
RA prognostic factors
Disease duration, years	11.2 ± 11.5	11.7 ± 11.7	10.6 ± 11.3	9.7 ± 10.2	0.07
Radiographic damage	52.4	52.5	51.6	53.4	0.93
DAS28	4.0 ± 1.6	3.9 ± 1.6	4.3 ± 1.6	4.3 ± 1.6	<0.001
MD-HAQ (0 to 3)	0.9 ± 0.6	0.9 ± 0.6	1.1 ± 0.6	1.1 ± 0.6	<0.001
RF positive, %	80.9	80.6	81.1	82.2	0.90
Anti-CCP positive, %	77.1	77.8	75.6	76.9	0.71
CRP (mg/L)	1.3 ± 2.0	1.4 ± 2.2	1.2 ± 1.7	1.0 ± 1.5	0.08
Prednisone, %	43.1	42.4	43.4	46.8	0.60
Methotrexate, %	51.2	53.0	47.0	50.0	0.18
Biologic agent, %	22.2	22.6	20.3	24.0	0.59
Age at diagnosis, years	52.1 ± 14.1	52.9 ± 14.6	51.3 ± 13.7	49.3 ± 11.4	0.005

Values shown are mean ± standard deviation (SD) of percentage; RA = rheumatoid arthritis; PTSD = post-traumatic stress disorder; HS = high school (12 years); BMI = body mass index; DAS28 = 28-joint Disease Activity Score; MD-HAQ = multidimensional Health Assessment Questionnaire; CRP = C-reactive protein; RF = rheumatoid factor; anti-CCP = anti–cyclic citrullinated peptide.

P values were generated as a global test for differences across groups using the chi-square test for categorical variables and one-way analysis of variance for continuous variables