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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Semin Arthritis Rheum. 2019 Feb 8;49(2):229–235. doi: 10.1016/j.semarthrit.2019.02.002

Table 1.

Characteristics of RA patients at the time of study enrollmenta

Total
(n = 1,460)
No psychiatric diagnosis
(n = 944)
Depression/Anxiety Without PTSD
(n = 346)
PTSD
(n = 170)
P valueb
Sociodemographics
 Age at enrollment, years 63.7 ± 11.3 64.9 ± 11.5 62.4 ± 11.4 59.3 ± 8.0 <0.001
 Men, % 90.8 91.6 88.7 90.6 0.28
 White, % 77.9 79.1 78.3 70.6 0.05
 ≥HS education, % 84.4 84.5 82.5 87.6 0.35
Other factors
 Comorbidity count (0 to 8) 1.8 ± 1.6 1.6 ± 1.5 2.3 ± 1.7 2.3 ± 1.6 <0.001
 Smoking status, % <0.001
  Never 20.4 21.7 19.7 15.3
  Former 52.3 54.5 52.6 40.0
  Current 27.2 23.9 27.8 44.7
 BMI (kg/m2) 28.3 ± 5.7 28.1 ± 5.7 28.1 ± 5.7 29.4 ± 5.9 0.05
RA prognostic factors
 Disease duration, years 11.2 ± 11.5 11.7 ± 11.7 10.6 ± 11.3 9.7 ± 10.2 0.07
 Radiographic damage 52.4 52.5 51.6 53.4 0.93
 DAS28 4.0 ± 1.6 3.9 ± 1.6 4.3 ± 1.6 4.3 ± 1.6 <0.001
 MD-HAQ (0 to 3) 0.9 ± 0.6 0.9 ± 0.6 1.1 ± 0.6 1.1 ± 0.6 <0.001
 RF positive, % 80.9 80.6 81.1 82.2 0.90
 Anti-CCP positive, % 77.1 77.8 75.6 76.9 0.71
 CRP (mg/L) 1.3 ± 2.0 1.4 ± 2.2 1.2 ± 1.7 1.0 ± 1.5 0.08
 Prednisone, % 43.1 42.4 43.4 46.8 0.60
 Methotrexate, % 51.2 53.0 47.0 50.0 0.18
 Biologic agent, % 22.2 22.6 20.3 24.0 0.59
 Age at diagnosis, years 52.1 ± 14.1 52.9 ± 14.6 51.3 ± 13.7 49.3 ± 11.4 0.005
a

Values shown are mean ± standard deviation (SD) of percentage; RA = rheumatoid arthritis; PTSD = post-traumatic stress disorder; HS = high school (12 years); BMI = body mass index; DAS28 = 28-joint Disease Activity Score; MD-HAQ = multidimensional Health Assessment Questionnaire; CRP = C-reactive protein; RF = rheumatoid factor; anti-CCP = anti–cyclic citrullinated peptide.

b

P values were generated as a global test for differences across groups using the chi-square test for categorical variables and one-way analysis of variance for continuous variables