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. Author manuscript; available in PMC: 2019 Nov 23.
Published in final edited form as: Ocul Surf. 2019 Feb 8;17(4):809–816. doi: 10.1016/j.jtos.2019.02.003

Table 1.

Gene Ontologies of upregulated genes by rosiglitazone in hMGEC.

GO_ID GO_ biological process description Item P_value FDR E_Score
GO:0030968 endoplasmic reticulum unfolded protein response 9 1.95E-09 3.52E-08 12.63
GO:0034976 response to endoplasmic reticulum stress 7 1.97E-05 2.88E-04 6.10
GO:0045766 positive regulation of angiogenesis 8 2.37E-05 3.38E-04 5.23
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 9 1.43E-05 2.12E-04 4.98
GO:0006461 protein complex assembly 7 3.55E-04 2.53E-03 4.05
GO:0018105 peptidyl-serine phosphorylation 8 1.75E-04 1.37E-03 4.04
GO:0030308 negative regulation of cell growth 7 4.56E-04 2.83E-03 3.90
GO:0001525 Angiogenesis 12 2.05E-05 2.97E-04 3.77
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 11 5.18E-05 6.94E-04 3.67
GO:0000165 MAPK cascade 14 1.94E-05 2.85E-04 3.39
GO:0046777 protein autophosphorylation 8 6.68E-04 3.52E-03 3.37
GO:0016569 covalent chromatin modification 13 7.46E-05 9.74E-04 3.16
GO:0006468 protein phosphorylation 25 5.38E-07 9.03E-06 2.92
GO:0016310 Phosphorylation 28 1.33E-07 2.30E-06 2.92
GO:0043065 positive regulation of apoptotic process 13 2.77E-04 2.06E-03 2.78
GO:0035556 intracellular signal transduction 17 7.17E-05 9.45E-04 2.70
GO:0010628 positive regulation of gene expression 13 5.07E-04 2.83E-03 2.62
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 24 4.64E-05 6.26E-04 2.32
GO:0016567 protein ubiquitination 18 3.61E-04 2.57E-03 2.30
GO:0006629 lipid metabolic process 17 6.09E-04 3.25E-03 2.26
GO:0043066 negative regulation of apoptotic process 17 6.47E-04 3.43E-03 2.25
GO:0055114 oxidation-reduction process 21 7.64E-04 3.93E-03 2.03