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. 2019 Aug;12(3):167–183. doi: 10.2174/1874467212666190304121131

Fig. (3).

Fig. (3)

Endogenous CBP and p300 expression in and the growth of wild type, CBP (+/-), and p300 (+/-) cells. 3T3 cells were generated from MEF cells that are heterozygous deficient for either CBP or p300. (a) Heterozygous CBP (+/-) MEFs express significantly less CBP than either wild type (WT) or p300 heterozygous p300 (+/-) cells as demonstrated by Western blot. Conversely, p300 (+/-) cells express considerably less p300 than the other two cell types. (b) p300 (+/-) 3T3 cells had a significantly steeper growth curve than either the WT or CBP (+/-) cells.