FIGURE 3.

Networks of direct protein-protein interactions with highlighted Golgi fragmentation-suppressing Rabs (A), Golgi-fragmenting Rabs and Kifs (B) and Golgi fragmentation-suppressing Kifs (C). Protein-protein interaction networks were constructed as described in Materials and Methods. Color code for the nodes: purple, hit Rabs and Kifs; yellow, direct interactors of the screening hits; cyan, proteins of tethering complexes; gray, proteins not forming direct interactions with the seed nodes. Edges colored in red represent direct interactions the seed nodes (suppressing Rabs, Golgi-fragmenting Rabs and Kifs or suppressing Kifs for (A–C), respectively) possess. See also Supplementary Table 5.