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. 2019 Aug 2;10:916. doi: 10.3389/fphys.2019.00916

Table 1.

Calibration criteria applied onto human ventricular cell models.

AP characteristic Min. acceptable value Max. acceptable value
Under baseline conditions (Guo et al., 2011; O'Hara et al., 2011 Britton et al., 2017)
APD90 (ms) 178.1 442.7
APD50 (ms) 106.6 349.4
RMP (mV) −94.4 −78.5
Vpeak (mV) 7.3
Under 90% IKs block (O'Hara et al., 2011)
ΔAPD90 (%) −54.4 62
Under 70% IKr block (Grandi et al., 2010)
ΔAPD90 (%) 34.25 91.94
Under 50% IK1 block (Jost et al., 2008)
ΔAPD90 (%) −5.26 14.86