Table 4.
Effects of mutation on stability of GUCY1A2 protein.
| Mutation | Stability | Reliability index | DDG (Kcal/mol) |
|---|---|---|---|
| R381Q | Decrease | 8 | −1.32 |
| G723S | Decrease | 8 | −0.97 |
| Q217H | Decrease | 6 | −0.62 |
| P676L | Increase | 1 | 1.17 |
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