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. 2019 Aug 7;39(32):6339–6353. doi: 10.1523/JNEUROSCI.2002-18.2019

Figure 8.

Figure 8.

Nav1.6 localization to the AIS of hippocampal CA1 neurons in ARF4+/−/ARF5−/− mice. A, B, Sagittal sections of postnatal week 8 WT (A) and ARF4+/−/ARF5−/− (B) mouse hippocampal CA1 regions were immunolabeled with an anti-Nav1.6 antibody (green) and an anti-ankyrin-G (magenta) antibody. Enlarged images from smaller rectangular white regions are shown in right lower insets. Scale bars, 10 μm. C, Immunoblot analysis of the P14 WT and Scn8atg/tg mice (Nav1.6-null mice). Protein lysates from the whole brain were immunoblotted with anti-Nav1.6 antibody. Arrowhead indicates the 229 kDa position.