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. 2019 Aug 6;4(4):e00305-19. doi: 10.1128/mSystems.00305-19

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Copyright © 2019 Fan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 5 — ZY-312 affects the intestinal bacterial communities in neonatal rats. The compositions of intestinal bacterial communities in neonatal rats were investigated using Illumina sequencing of the 16S rRNA gene (n = 3 in each group). (A) PCoA data based on OTUs in all groups. (B) Rarefaction curve showing the relative abundances of OTUs in all groups. (C) Relative abundances of the most abundant bacterial phyla in different groups. (D) Significantly different bacterial biomarkers, determined by the least discriminant analysis (LDA) effect size, were identified in C. sakazakii relative to the control group. (E) A heat map constructed with the top 35 most abundant genera.