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Cis genotype was significantly associated with CYP2E1 but not IRS2 DMR methylation levels.( A) CYP2E1 genotype at rs1536828 within the ASD DMR was significantly associated with CYP2E1 DMR average percent methylation tested by ANOVA (P = 0.03). (B) IRS2 genotype at rs9301411 within the ASD DMR was not significantly associated with IRS2 DMR methylation by two-tailed t-test (P = 0.86).
