Table 2.

Influence of digitoxin on implantation and growth of metastases-like tumors from cells administered by intravenous route.

Prostate cancer cells and digitoxin both given on day 0 for 10 days	Primary tumor	Mz number	Mz diameter, mm		Mz Area, mm2		Total Mz Area
			Average	Median	Average	Median
Digitoxin-treated (n = 14 rats)
Average	–	122	1.79	1.76	2.76	2.50	390
Median	–	127	1.80	1.77	2.72	2.46	327
SD	–	78	0.31	0.29	0.92	0.79	294
Sem	–	21	0.08	0.08	0.24	0.21	78
Control (n = 14 rats)
Average	–	129	2.10	2.07	3.79	3.43	526
Median	–	131	2.07	2.07	3.53	3.37	498
SD	–	64	0.34	0.33	1.16	1.00	317
Sem	–	17	0.09	0.09	0.31	0.27	85
Comparison
Control vs. Digitoxin-treated
Ratio of averages	–	1.05	1.17	1.17	1.37	1.37	1.35
Ratio of medians	–	1.03	1.14	1.17	1.30	1.37	1.52
Student's t-test (1–tailed)	–	0.411	0.009	0.008	0.008	0.005	0.125
Mann-Whitney test (1–tailed)	–	0.492	0.005	0.003	0.005	0.003	0.104