Table 2. AGREE II domain scores and overall assessment of the included VAP guidelines.
| Guideline | Score of the Six AGREE II Domains (%) | Overall assessment | |||||
|---|---|---|---|---|---|---|---|
| Scope and purpose | Stakeholder involvement | Rigor of development | Clarity and presentation | Applicability | Editorial independence | ||
| Dodek 2004 (19) | 51 | 42 | 52 | 54 | 39 | 77 | Recommended with modification |
| Muscedere 2008a (20) | 60 | 40 | 53 | 53 | 45 | 77 | Recommended with modification |
| Muscedere 2008b (21) | 60 | 40 | 52 | 54 | 45 | 77 | Recommended with modification |
| Masterton 2008 (22) | 58 | 26 | 36 | 47 | 28 | 65 | Recommended with modification |
| Rotstein 2008 (23) | 58 | 21 | 31 | 57 | 35 | 42 | Recommended with modification |
| Morrow 2009 (24) | 63 | 25 | 22 | 56 | 25 | 29 | Recommended with modification |
| Gupta 2012 (25) | 58 | 26 | 39 | 57 | 40 | 38 | Recommended with modification |
| Li 2013 (3) | 54 | 18 | 52 | 57 | 26 | 0 | Recommended with modification |
| Klompas 2014 (26) | 58 | 28 | 23 | 47 | 30 | 67 | Recommended with modification |
| Kalil 2016 (27) | 71 | 68 | 55 | 71 | 52 | 77 | Recommended |
| Mikasa 2016 (28) | 65 | 40 | 35 | 61 | 43 | 33 | Recommended with modification |
| Torres 2017 (29) | 74 | 57 | 59 | 67 | 59 | 65 | Recommended |
| Qu 2018 (1) | 64 | 33 | 30 | 53 | 21 | 0 | Recommended with modification |
| Totala | 61 [51–74] | 36 [18–68] | 41 [22–59] | 56 [47–71] | 38 [21–52] | 50 [0–77] | |
a, data were presented as mean [range]. AGREE, Appraisal of Guidelines for Research and Evaluation; VAP, ventilator-associated pneumonia.