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. 2019 Jul;11(7):3015–3029. doi: 10.21037/jtd.2019.07.50

Table 2. Clinical characteristics of the ESCC patients included in GEO.

Clinical characteristics N Relative expression of miR-30b-5p
Mean ± SD t P
Gender −1.516 0.132
   Male 98 0.80±0.41
   Female 21 0.96±0.55
Age, years −1.418 0.159
   ≥60 58 0.77±0.34
   <60 61 0.88±0.51
Family history 0.525 0.605
   Positive 42 0.89±0.67
   Negative 40 0.81±0.37
Tobacco −0.302 0.763
   Yes 80 0.82±0.41
   No 39 0.85±0.50
Alcohol −1.085 0.280
   Yes 74 0.79±0.38
   No 45 0.88±0.52
Tumor Location F=0.608a 0.546
   Upper 14 0.82±0.45
   Middle 69 0.86±0.48
   Lower 36 0.76±0.34
Tumor Grade F=1.645a 0.198
   Well 23 0.73±0.31
   Moderately 64 0.81±0.39
   Poorly 32 0.94±0.58
T status F=0.054a 0.054
   T1 8 1.13±0.32
   T2 20 0.64±0.46
   T3 62 0.83±0.37
   T4 29 0.87±0.53
N status F=1.995a 0.119
   N0 54 0.76±0.44
   N1 42 0.88±0.38
   N2 13 0.75±0.44
   N3 10 1.08±0.56
TNM F=1.312a 0.273
   I 6 0.90±0.39
   II 47 0.75±0.38
   III 66 0.88±0.48

a, one-way analysis of variance (ANOVA) test was utilized. GEO, Gene Expression Omnibus; SD, standard deviation; t, Student’s t-test; ESCC, esophageal squamous cell carcinoma.