Table 2. Clinical characteristics of the ESCC patients included in GEO.
| Clinical characteristics | N | Relative expression of miR-30b-5p | ||
|---|---|---|---|---|
| Mean ± SD | t | P | ||
| Gender | −1.516 | 0.132 | ||
| Male | 98 | 0.80±0.41 | ||
| Female | 21 | 0.96±0.55 | ||
| Age, years | −1.418 | 0.159 | ||
| ≥60 | 58 | 0.77±0.34 | ||
| <60 | 61 | 0.88±0.51 | ||
| Family history | 0.525 | 0.605 | ||
| Positive | 42 | 0.89±0.67 | ||
| Negative | 40 | 0.81±0.37 | ||
| Tobacco | −0.302 | 0.763 | ||
| Yes | 80 | 0.82±0.41 | ||
| No | 39 | 0.85±0.50 | ||
| Alcohol | −1.085 | 0.280 | ||
| Yes | 74 | 0.79±0.38 | ||
| No | 45 | 0.88±0.52 | ||
| Tumor Location | F=0.608a | 0.546 | ||
| Upper | 14 | 0.82±0.45 | ||
| Middle | 69 | 0.86±0.48 | ||
| Lower | 36 | 0.76±0.34 | ||
| Tumor Grade | F=1.645a | 0.198 | ||
| Well | 23 | 0.73±0.31 | ||
| Moderately | 64 | 0.81±0.39 | ||
| Poorly | 32 | 0.94±0.58 | ||
| T status | F=0.054a | 0.054 | ||
| T1 | 8 | 1.13±0.32 | ||
| T2 | 20 | 0.64±0.46 | ||
| T3 | 62 | 0.83±0.37 | ||
| T4 | 29 | 0.87±0.53 | ||
| N status | F=1.995a | 0.119 | ||
| N0 | 54 | 0.76±0.44 | ||
| N1 | 42 | 0.88±0.38 | ||
| N2 | 13 | 0.75±0.44 | ||
| N3 | 10 | 1.08±0.56 | ||
| TNM | F=1.312a | 0.273 | ||
| I | 6 | 0.90±0.39 | ||
| II | 47 | 0.75±0.38 | ||
| III | 66 | 0.88±0.48 | ||
a, one-way analysis of variance (ANOVA) test was utilized. GEO, Gene Expression Omnibus; SD, standard deviation; t, Student’s t-test; ESCC, esophageal squamous cell carcinoma.