Table 5. Comparisons of the 8th edition stage patients with and without stage migration from 7th edition staging system.
7th edition | 8th edition | OS | RFS | |||||
---|---|---|---|---|---|---|---|---|
Event/N | P | HR (95% CI) | Event/N | P | HR (95% CI) | |||
IB | IB | 189/805 | – | 1 | 185/805 | – | 1 | |
IIA | 58/186 | 0.048 | 1.34 (1.01–1.81) | 51/186 | 0.042 | 1.36 (1.02–1.86) | ||
IIB | IIB | 55/138 | – | 1 | 43/138 | – | 1 | |
IIIA | 69/135 | 0.040 | 1.46 (1.02–2.09) | 67/135 | <0.001 | 1.97 (1.32–2.94) | ||
IIIA | IIIA | 307/541 | – | 1 | 286/541 | – | 1 | |
IIIB | 98/147 | 0.006 | 1.38 (1.10–1.73) | 94/147 | <0.001 | 1.58 (1.25–2.00) |
All the results were adjusted by age (≥70 vs. <70 years) and sex for overall survival and by age, histology, and history of adjuvant therapy for recurrence-free survival. OS, overall survival; RFS, recurrence-free survival; HR, hazard ratio; CI, confidence interval.